From dark days of HIV-AIDS, advances in chemistry enable breakthrough treatment — and other chemical innovations

Yale.edu - January 26, 2026

From dark days of HIV-AIDS, advances in chemistry enable breakthrough treatment — and other chemical innovations

Research by Yale chemist and pharmacologist Jon Ellman has spawned at least 10 FDA-approved drugs and agrochemicals — and enabled the breakthrough HIV-AIDS treatment lenacapavir, which was named “2024 Breakthrough of the Year” by Science magazine.

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